HELIOS
Making genomics pipelines reproducible — with signed audit trails, machine-readable evidence, and compliance-oriented checks. Apache-2.0, free.
Apache-2.0 core · early alpha · commercial support & dashboard hosting
Why HELIOS exists
Reproducibility in genomics usually fails not at the science — but at the documentation. Which container version? Which reference? Which input? HELIOS records that, signs it, and exports it in verifiable formats (JSON, PDF, RO-Crate). Not as a promise — as technical evidence.
How we offer it
Core framework: open source under Apache License 2.0. You can adopt the CLI and libraries in your own environment, inspect the code, and extend checks—same spirit as our other Apache-2.0 tooling.
Commercial: Synaptic Four offers paid support (onboarding, prioritised fixes, integration help) and optional hosted dashboard operations for organisations that want a managed UI and service-level expectations. Details are agreed per engagement; the public repository remains the source of truth for the OSS core.
Who it fits
- Clinical genomics and high-throughput labs documenting validation and software controls (e.g. themes aligned with ISO 15189:2022—still your QMS and your accreditation path).
- Teams that already use GA4GH-oriented stacks and want audit exports and reference integrity checks that interoperate with broader ecosystem expectations.
- Programmes that need technical documentation and data-governance artefacts in EU AI Act conversations (Articles 10/11 themes)—engineering evidence, not a legal verdict.
Evidence for auditors and partners
HELIOS is built so technical owners can show what ran, with what inputs, and which checks fired—without claiming that your organisation is certified.
- Signed, exportable run records (JSON, PDF, RO-Crate) that procurement and quality teams can attach to their own QMS folders.
- Compliance-oriented checks and reference-integrity signals you can reproduce from the public repository—not a vendor attestation.
Orientation, not certification
HELIOS produces structured technical evidence for your QMS. It does not certify your lab, replace qualified sign-off, or convert optional support into a regulatory approval.
Pricing (indicative)
The Apache-2.0 core is free and stays free. For support or hosting:
| Service | Guide |
|---|---|
| Support (onboarding + 12 months prioritised support) | from €3,000/year |
| Dashboard hosting (managed, incl. updates) | from €300/month |
| Integration support (project-based) | €800–1,200/day — first pilot free by arrangement |
All prices net, plus VAT. Binding terms agreed in writing.
What HELIOS is not
- Not a certification, accreditation, or regulatory approval by itself.
- Not a substitute for your quality manager, notified body, or counsel when those roles are required.
- Not a promise that any specific checklist item is “done”—it produces structured evidence you still must interpret in your QMS.
Alpha: install from the GitHub repository until a tagged PyPI release exists (planned package name: helios-audit). Not a certification product.
Also relevant
HELIOS audit trails sit naturally beside Ferrum’s GA4GH plane and Solum’s clinical compliance evidence — same engagement conversation when both planes matter.